Glycolysis
GlycolysisGlycolysis the first stage of cellular respiration; it is a metabolic pathway that happens within the cytosol of the cell. In this pathway you start the breakdown of glucose in a series of ten reactions to ultimately create two pyruvate molecules needed for the next stage of cellular respiration. How does this occur? Two ATP molecules are used to add a phosphates our glucose molecules in the first half of the pathway. Once this is done and glucose has become fructose 1,6-bisphophate, this molecule is split into dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P) . Than immediately an enzyme converts DHAP into G3P and you now have 2 molecules of G3P. The second half of the pathway, steps 6 through 10 happens twice. The G3P has NAD come in take away hydrogen and become NADH, which makes 1-3 bisphosphoglycerate (BPG) . When BPG is converted to 3-phosphoglycerate (3PG) a ATP molecule is made. Then 3PG becomes 2-phosphoglycerate (2PG). Once 2PG has been made it is converted to phosphoenolpyruvate (PEP), during this conversion water is taken out. Then in the final step PEP is converted to pyruvate and creates ATP during that last reaction.
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Teaching resources
Below are a few teaching resources that one can use to help reinforce glycolysis for students
HOOK
Use this as an interesting hook that will help peek interest of the students
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Student worksheet
Received from L.Philips
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Activities
Glycolysis Challenge
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Students are put into a group that work as a tag team to write down glycolysis on the board as correctly as possible. Each student has a certain amount of time to get as much of the pathway onto the board before the teacher rings the bell and the next student in their group runs up to fill in the rest. This continues till time is completely out. |
assessment
Help reinforce and check student understanding can conduct the quiz as a class or allows students to have laptops or time in computer lab to do this quiz. Can give feedback as students write quiz to ensure no student is left behind. Also there is a link for a animation that can be used as reinforcement for when you have finished teaching glycolysis.
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