Overview of protein synthesis
Background Knowledge
Prior to the topic of protein synthesis being covered within the classroom setting, students should have already been taught the unit on Biochemistry and the curriculum expectations covering DNA. The slideshow below provides a brief overview of protein synthesis and highlights which concepts should be covered for this topic (note the pages titled "Transcription" and "Translation" will cover the content that is in the PowerPoint below in greater detail) .
When covering this topic with your students, I would suggest introducing the content as a big picture by going over the Central Dogma of Molecular Biology. I would then break down the various aspects of the Central Dogma and cover them in greater detail. At the end, you can then recap the content with your students by going over the Central Dogma of Molecular Biology once more; however, you can now provide your students with more detail then the initial generalized big picture that you had gone over at the start (see below).
When covering this topic with your students, I would suggest introducing the content as a big picture by going over the Central Dogma of Molecular Biology. I would then break down the various aspects of the Central Dogma and cover them in greater detail. At the end, you can then recap the content with your students by going over the Central Dogma of Molecular Biology once more; however, you can now provide your students with more detail then the initial generalized big picture that you had gone over at the start (see below).
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Protein Synthesis.pptx | |
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File Type: | pptx |
Central Dogma of Molecular Biology
An Introduction to Protein Synthesis
When you begin to introduce the topic of Protein Synthesis to your class, it is a good idea to start with the big picture by going over the Central Dogma of Molecular Biology with your students. This concept is important as it provides an explanation of how ribosomes can synthesize proteins without the DNA having to leave the nucleus, which would lead to too many complications.
With this in mind, you could pose a higher order thinking question to your students, asking them "why should DNA remain within the nucleus?" This question should lead to a discussion about how DNA is required for the cell to function normally and thus, allowing it to leave the nucleus and enter the more caustic environment of the cytoplasm could lead to the DNA being damaged .
With this in mind, you could pose a higher order thinking question to your students, asking them "why should DNA remain within the nucleus?" This question should lead to a discussion about how DNA is required for the cell to function normally and thus, allowing it to leave the nucleus and enter the more caustic environment of the cytoplasm could lead to the DNA being damaged .
A Recap of Protein Synthesis
After covering the process of Transcription and Translation with your students in greater detail, you can then refer back to the Central Dogma of Molecular Biology in order to review the steps of protein synthesis. Now that your students will have more knowledge about the different steps that occur within the Central Dogma, you can then expand on it in order to emphasize the genetic language that they should be using (see image below).